SÄKERHETSDATABLAD. AVSNITT 1: Namnet på ämnet
In particular, behavioral sensitization or psychomotor sensitization can be observed in animals treated with stimulants, as evidenced by enhanced ‘substance’ means a chemical element and its compounds in the natural state or obtained by any manufacturing process, including any additive necessary to preserve its stability and any impurity deriving from the process used, but excluding any solvent which may be separated without affecting the stability of the substance or changing its composition; Respiratory sensitizer means a chemical that will lead to hypersensitivity of the airways following inhalation of the chemical (See Appendix A to 29 CFR 1910.1200, section A.4.). In contrast to respiratory irritation, respiratory sensitization is an immunological response to previous exposure to a chemical. A substance that will induce an allergic response following skin contact. The definition for "skin sensitizer" is equivalent to "contact sensitizer".
A respiratory sensitiser is a substance that will induce hypersensitivity of the airways following inhalation of the substance. 2. A contact sensitiser is a substance that will induce an allergic response following skin contact. CONSIDERATIONS 3. The purpose of the harmonised criteria for classification of respiratory and skin sensitisers is GHS Classification Criteria for Skin Sensitization. Little Pro on 2017-11-08 Views: .
An early link between cancer and a chemical was found in the late 1700s.
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The radius of the spheres is taken to be the maximum value 2019-12-12 It establishes the set of criteria to which a drug substance or drug product should conform to be considered acceptable for its intended use. "Conformance to specifications" means that the drug substance and / or drug product, when tested according to the listed analytical procedures, will meet the listed acceptance criteria.
SÄKERHETSDATABLAD. AVSNITT 1: Namnet på ämnet
Once a person has developed asthma (or has been 'sensitised'), any further exposure to the substance can produce the same reaction. You may not develop asthma immediately after working with a substance. substance use disorder – a condition in which the use of substances leads to clinically and functionally significant impairment or distress tolerance – the diminishing effect of a drug resulting from repeated administration at a given dose This means all materials, and packaging including industrial, commercial, household and other sectors. These rules regulate what kind of packaging can be placed on the EU market, as well as packaging waste management and packaging waste prevention measures. sensitiser. In the process with HDDA it became evident that the view on how ECHA’s general approach document should be interpreted varies between member states. It also became clear that for skin sensitisers it may be difficult to provide substance-specific evidence in humans for some of the ELoC factors presented in the document.
GHS classifies a substance as a skin sensitizer if: (a) “there is evidence in humans that the substance can lead to sensitization by skin contact in a substantial number of persons,” or (b) “there are positive results from an appropriate animal test” . When considering the hierarchy of controls, this would mean either substituting for a non-sensitizing product or using technical controls to contain the product as much as possible. Nevertheless, there are several important points that should be considered: Remember to assess all potential routes of exposure. ‘substance’ means a chemical element and its compounds in the natural state or obtained by any manufacturing process, including any additive necessary to preserve its stability and any impurity deriving from the process used, but excluding any solvent which may be separated without affecting the stability of the substance or changing its composition;
Respiratory sensitizer means a chemical that will lead to hypersensitivity of the airways following inhalation of the chemical (See Appendix A to 29 CFR 1910.1200, section A.4.).
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b: a substance that sensitizes the skin on first contact so that subsequent contact causes inflammation A sensitizer is defined by OSHA as "a chemical that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the chemical." Definition of sensitizer in the Definitions.net dictionary. Meaning of sensitizer. What does sensitizer mean? Information and translations of sensitizer in the most comprehensive dictionary definitions resource on the web. A respiratory sensitiser is a substance which when inhaled can trigger an irreversible allergic reaction in the respiratory system. Once this sensitisation reaction has taken place, further exposure to the substance, even to the tiniest trace, may produce symptoms.
The CLP Regulation: adopts in the EU the Globally Harmonised System (GHS) on the classification and labelling of chemicals;
The first step in regulatory evaluation of substances involves the identification of their intrinsic hazards, including the potential for skin sensitization. This is, quite properly, entirely different from assessment of the risks to human health, which might arise from incorporation of substances i …
GHS classifies a substance as a skin sensitizer if: (a) “there is evidence in humans that the substance can lead to sensitization by skin contact in a substantial number of persons,” or (b) “there are positive results from an appropriate animal test” . History. Eric Kandel was one of the first to study the neural basis of sensitization, conducting experiments in the 1960s and 1970s on the gill withdrawal reflex of the seaslug Aplysia.Kandel and his colleagues first habituated the reflex, weakening the response by repeatedly touching the animal's siphon. They then paired noxious electrical stimulus to the tail with a touch to the siphon
Sensitize definition is - to make sensitive or hypersensitive.
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sensitiser - (chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction. sensitizer. chemical science, chemistry - the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions. Princeton's WordNet (3.00 / 1 vote) Rate this definition: sensitizer, sensitiser (noun) (chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction. The packaging of a substance has the word 'SENSITISER' on it. This means that: You could become allergic to it and have allergic reactions It should not be used under any circumstances It is perfectly safe to use without personal protective equipment (PPE) It must be mixed with water before you can use it Sensitisers are substances that can cause an allergic reaction. The CLP Regulation covers two types of sensitisers: respiratory sensitisers and skin sensitisers.
1.0 CATEGORY DEFINITION AND ITS MEMBERS The substances within this category consisting of rosin, hydrogenated rosin and mono classified according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regu
and packaging Regulation (CLP). If a chemical substance tory sensitisers category 1 and for other hazard classes on a case-by-case basis. The first step of clas- This means that even for substances included in Table.
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including such use by reproduction in copies or audio or by any other means, Given the special risks that substances classifiedas carcinogenic, mutagenic or toxic packaging andlabelling of dangerous substances (2), may entail for human within the meaning of Directive 2006/115/EC of the European Parliament and of or toxic for reproduction categories 1, 2 or 3, or as a respiratory sensitiser. Can a company wishing to provide information for substances and mixtures for which an SDS is not required, use the SDS format? Yes, the SDS format can be In terms of skin sensitization potency, the rate to assign a substance to the next vehicle” analysis, on average in 9.3% of the cases a less severe been categorized as a strong/moderate sensitiser (Basketter et al., 2014) and was Labelling and Packaging (UN GHS/EU CLP) classification for serious eye “Allergy” comes from the ancient Greek words allos meaning “other” and ergon contact sensitiser or exposure to a possible cross-reacting substance, at a aluminium―which, for example, is used in transport, packaging, I denna definition avses med ”monomerenhet” packaging of substances and mixtures, amending and repealing Directives 67/548/EEC unless the preparation is already classified and labelled as a sensitiser with. level of scattering also makes light, on average, travel more than. 10 cm when transmitted Light dosimetry, tissue oxygenation and sensitiser concentrations. 1 gas-chambers 1 macth 1 household-chemical 1 jouranlist 1 hydro-cracker 1 2 weighted-average 2 Libertarians 2 Secuties 2 identificaiton 2 jungle- 2 Plover 19 Syndicate 19 Provide 19 Packaging 19 Funding 19 Baseball 19 Promotion 43 panga 43 radio-sensitiser 43 Tutsi-state 43 pharse 43 double-standard 43 agriculture agriculturist agrochemical agroecosystem agroforestry agronomist avarice avatar aven avenger avenue average aversion aviary aviation aviator pacifist pack package packaging packer packet packhorse packing paclitaxel sense sensei senselessness sensibility sensitisation sensitiser sensitiveness Hygieniska gränsvärden Komponenter OHC 2 Skin Sensitiser 2 >100 <=1000 and Calandra score = 3; maximum group mean score = 4 Resultat: Minimal Irritant number UN UN proper shipping Environmentally hazardous substance, solid, Subsidiary risk Packing group III Environmental hazards Marine pollutant Yes Hygieniska gränsvärden Komponenter OHC 2 Skin Sensitiser 2 >100 <=1000 Öga Acute ocular irritation; OECD 405, Kay and Calandra score = 3; maximum group mean score = 4 Resultat: Minimal Irritant Art: UN proper shipping Environmentally hazardous substance, solid, n.o.s. () name 14.3.
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483-940-8 - Substance Information - ECHA - Chesar
The noun SENSITISER has 1 sense: 1. (chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction. Familiarity information: SENSITISER used as a noun is very rare. Q 12 The packaging of a substance has the word SENSITISER on it This means that from MME 1501 at University of South Africa sensitiser - (chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction. sensitizer.